Extranodal Rosai-Dorfman disease of the kidney

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Extranodal Rosai-Dorfman disease of the kidney

Ann Saudi Med 29(1) January-February 2009 www.saudiannals.net 55 Lampert and Lennert in 1961 were the first to describe what is now known as Rosai-Dorfman disease (RDD). Subsequently in 1969, Rosai and Dorfman described 4 cases of a disease they called sinus histocytosis with massive lymphadenopathy (better known as RDD).1 In 1972 they analyzed 30 additional cases, establishing RDD2 as a clinic...

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Rosai-Dorfman disease with extranodal involvement.

Rosai-Dorfman disease is a rare condition of marrow hematopoietic stem-cell origin. Patients can show extranodal involvement as well as lymphatic involvement, but only about 5% of extranodal cases involve intracranial lesions. A 53-year-old male was admitted to our hospital with bilateral cervical lymphadenopathy. Intracranial tumors and bone lesions were also detected. Cervical lymph node biop...

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Extranodal manifestation of Rosai-Dorfman disease in the breast tissue

A 71-year-old asymptomatic female with a history of breast cancer status after right total mastectomy had interval development of several new nodules in the left breast in a 1-year time span. Stereotactic biopsy was performed, which revealed multifocal Rosai Dorfman disease in the left breast. The patient was referred to hematology, and computed tomography of the chest/abdomen/pelvis did not de...

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Extranodal Rosai-Dorfman disease involving the pulmonary artery.

A 61-year-old woman underwent computed tomography (CT) angiography for evaluation of syncope and was found to have a central pulmonary artery filling defect (Fig. 1). During an attempted intravascular ultrasound-guided biopsy of the lesion, the patient coded and died. Autopsy confirmed the case as a rare presentation of Rosai-Dorfman disease (Fig. 2 and Supplementary Figs 1 and 2). Supplementar...

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Diagnosis of multifocal extranodal Rosai Dorfman disease Case Study

Rosai-Dorfman Disease (RDD) or sinus histiocytosis with massive lymhadenopathy is a rare, nonneoplastic proliferative disorder of the cells of macrophage-histiocyte family having a self limiting course. Though it affects lymphnodes commonly, it can also involve many extranodal sites. These cases can often be misdiagnosed as lymphoma. Therefore, one has to be very careful not to interpret it as ...

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ژورنال

عنوان ژورنال: Annals of Saudi Medicine

سال: 2009

ISSN: 0256-4947,0975-4466

DOI: 10.4103/0256-4947.51823